Treatment with rectal tacrolimus for eight weeks can lead to a clinical response in nearly three-fourths of patients with refractory ulcerative proctitis, researchers have found.
The study showed such marked improvements using topical tacrolimus compared with placebo that it was terminated early, according to the investigators, who presented their finding at the 2017 annual meeting of the European Crohn’s and Colitis Organisation (abstract OP007).
“Although this is a small trial, the